Age-Associated Hormone Changes:
Clinical Issues for Men
As men age, their ability to produce testosterone declines, while the production of a protein that tightly binds testosterone increases. This results in reduced levels of bioavailable, or free, testosterone in the blood that can be utilized by bodily tissues such as the muscles, bones, and the heart. At the same time, many men develop an imbalance in estrogen and testosterone metabolites.
These changes in hormone levels can be associated with a variety of clinical issues.
Mood. A decline in free testosterone has been implicated in mood swings and cognitive concerns.
Muscle tone. Testosterone levels have been positively correlated with muscle tone and strength.
Sexual function. A decline in testosterone levels may be indicated by libido or sexual function issues.
Cardiovascular health. Altered hormone metabolism can influence not only cholesterol, but also triglycerides and cardiovascular disease risk.
Prostate health. Changes in hormone levels, such as an increase in DHT (testosterone metabolite) or a decrease in 2-OH, have been linked to prostate health concerns.
Hair patterns. High DHT levels have been associated with male pattern baldness.
Breast appearance. Either increased levels of estrogen or altered ratios of testosterone-to-estrogen have been linked to apparent breast enlargement.
Colon Health. Estrogen has been implicated in the development of colon health concerns.
Mood & Memory Hair Patterns Energy & Endurance
Breast Appearance Colon Health Prostate Health Sexual Function Bone Health
Muscle Tone Immune Health Cardiovascular Health
Metagenics provides specialized nutritional
support for men’s age-related health challenges.
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